Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis
نویسندگان
چکیده
منابع مشابه
Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis
Wnt regulates bone formation through β-catenin-dependent canonical and -independent noncanonical signaling pathways. However, the cooperation that exists between the two signaling pathways during osteoblastogenesis remains to be elucidated. Here, we showed that the lack of Wnt5a in osteoblast-lineage cells impaired Wnt/β-catenin signaling due to the reduced expression of Lrp5 and Lrp6. Pretreat...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2014
ISSN: 2045-2322
DOI: 10.1038/srep04493